CombiMatrix (CBMX) is an
ETF Innovators
Emerging
Diagnostics Index component and spin-off company from Acacia Research (ACTG)
which has operated independently since August 2007 as a developer of DNA
MicroArrays for lab-based personalized medicine applications to improve
treatment outcomes, which are exempt from the more time-consuming and costly
route of FDA approval as in vitro diagnostic products. The tests are also
affordable, with a target price of $250-$300 on average.
Today, CBMX announced a four-year contract with NASA's Ames Research Center
that includes $214,051 in funding for the first year with three additional
option years at the same level of funding. The Company will provide NASA with a
molecular diagnostics package that will be used to study genetic changes in
bacteria as they orbit around the earth. CBMX has developed a diagnostic array
reader which is the size of a mobile phone and an expected launch during 3Q09.
Earlier this month, CBMX reported its results for 4Q and FY08, which included
a 208% increase in diagnostic lab revenue from the year-ago period, a 29%
sequential increase in diagnostic lab revenue, and positive data on the
Comprehensive Cancer Array (CCA) test (with an expected launch in 2010).
Last month, preliminary results for the CCA test demonstrated that it can
non-invasively screen for the early detection of cancer, focusing on prostate,
colon, ovarian, breast, and lung cancers (which account for about 85% of all
solid tumors in the U.S.). The study showed that the miRNA (type of nucleic
acid) expression patterns in the blood for patients with cancer (including early
stage 1) were very different from patients who were cancer-free. An analysis of
results indicated that a clear distinction could be made between patients with
cancer and those without.
A broad-based, early detection test for cancer would have tremendous market
potential and fits well with the focus on preventive medicine by the new
administration. This early warning system for cancer is designed to be a
non-invasive, blood screening test which would require confirmation of results
by a follow-up, invasive method such as a biopsy.
CBMX reported 4Q08 revenue of $1.2M, operating expenses of $5.2M, and a net
loss of $4.1M versus year-ago results for these metrics of $1.9M, $5.5M, and
$3.5M, respectively.