Health care shares are mixed in the pre-market session. Cell Genesys (CEGE) is higher after BioSante Pharmaceuticals (BPAX) stockholders approved the companies' merger. Halozyme Therapeutics (HALO) is higher after announcing additional Phase 2 results demonstrated faster insulin absorption and increased peak insulin concentrations in type 1 diabetic patients after co-administration of its recombinant hyaluronidase enzyme with Humulin R (regular human insulin), a mealtime insulin. Cell Therapeutics (CTIC) is higher after announcing that patients with cancer of the lower esophagus demonstrated a high rate of complete remission when given Opaxio (paclitaxel poliglumex), a biologically enhanced paclitaxel, when administered in combination with standard cisplatin and concurrent radiation.

Cell Genesys said BioSante Pharmaceuticals stockholders have approved the companies' merger.

Halozyme Therapeutics said additional Phase 2 results demonstrated faster insulin absorption and increased peak insulin concentrations in type 1 diabetic patients after co-administration of its recombinant hyaluronidase enzyme with Humulin R (regular human insulin), a mealtime insulin. In addition, study results also showed a significant reduction in postprandial blood glucose levels following administration of a standardized test meal and less hypoglycemia compared to Humulin R alone.

Cell Therapeutics announced that patients in a study with cancer of the lower esophagus demonstrated a high rate of complete remission when given Opaxio (paclitaxel poliglumex), a biologically enhanced paclitaxel, when administered in combination with standard cisplatin and concurrent radiation.

Dow Jones U.S. Health Care Index: -1.40 (-0.47%) at 296.33 (Wednesday regular session close)

Top Health Care Stocks:

JNJ: -0.07%

PFE: -0.06%

ABT: +0.06%

MRK: +0.19%

WYE: +0.04%

UPSIDE MOVERS

Vical (VICL): Stock is recently bouncing up from a pre-market low of 4.37, seeing strong upside liquidity off this bottom. Longs may want to watch the 4.37 to 4.40 area into the open to see if it holds as a floor support - a level that could see upside movement back into the higher 4.40s or possibly breach 4.50.

DOWNSIDE MOVERS

RADVision (RVSN): Stock is stretching to fresh pre-market lows late in the session, sliding from 7 to 6.61. RVSN developed two distinct ceiling levels in the pre-market session, at 7.30 to 7.20 and at 7.10 to 7.00 - areas shorts may want to eye as a potential near-term top. More risk tolerant shorts might want to target the 6.80 to 6.70 area, a ceiling level developing late in this morning's session.