KJ VENLO, GERMANY -- (Marketwire) -- 11/06/08 --

Worldwide license agreement expands the Company's veterinary assay portfolio and aims to contain future outbreaks of the devastating viral disease

Venlo, The Netherlands - November 6, 2008 - QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) has announced today that it has entered into a worldwide exclusive partnership with the Institute for Animal Health (IAH), a leading research and diagnostics institution for infectious diseases of farm animals. Pursuant to the agreement QIAGEN has licensed a novel molecular assay design for bluetongue, a devastating viral disease among ruminants such as sheep and cattle. The cador BTV RT-PCR Kit, which was developed by the IAH, will be launched by QIAGEN in 2009 and further expand the company's veterinary testing portfolio.

Bluetongue is caused by the bluetongue virus (BTV). It mainly afflicts cattle and sheep which exhibit the highest morbidity and mortality rates reaching up to 70 percent. Since 1998, the disease has been rapidly spreading throughout Europe with outbreaks in most countries including the United Kingdom, Spain, Italy, Greece, Belgium, The Netherlands, Germany and France. In 2008 alone, 16 outbreaks of the disease have been registered across Europe. Currently authorities in the Netherlands and several other countries in Europe are struggling to contain outbreaks caused by a BTV type 8, previously only found in Central and South America, and Africa. The IAH estimates the potential economic impact of a major bluetongue outbreak to exceed EUR 600 million in the U.K. alone - resulting from increased mortality rates, losses in milk production, export and animal movement restrictions. Containment and therefore early detection tools are key to combat this disease.

The new cador BTV RT-PCR Kit allows fast and highly sensitive detection of all 24 known strains of the bluetongue virus; including BTV-6 which has caused the latest outbreak of the disease in the Netherlands, and BTV-1, which has spread from North Africa, up to the north coast of France, threatening the UK. Because many symptoms of bluetongue are not specific to the disease, there is a growing demand for reliable and fast laboratory tests which might help to contain future outbreaks.

"The emergence and dissemination of new BTV strains currently observed in Europe pose a serious threat to the agricultural industry. The new cador BTV RT-PCR can help to contain future outbreaks of the disease, and thereby minimize the risk of major economic damage", explains Simone Gauch, Global Marketing Director Applied Testing at QIAGEN. "A major advantage of the test is that it detects all known serotypes of the virus as well as variants from different parts of the world. The test can be used to test vaccinated animals, which are usually only protected against the limited number of BTV types addressed by the vaccine, and thus animals still need to be screened as soon as they exhibit any symptoms. This has been impossible using traditional diagnostic methods, because the antibodies present in vaccinated animals are too similar to antigens produced during a new infection.