Northfield Laboratories Inc. (Nasdaq: NFLD) will host its second quarter 2009 earnings conference call with the financial community on Monday, January 12, 2009 at 11:00 a.m. Eastern Time (10 a.m. Central Time).

This call is being webcast by Thomson Reuters and can be accessed at Northfield's Web site at http://www.northfieldlabs.com. A replay will be available in the same location for two weeks following the call.

The webcast is also being distributed through the Thomson StreetEvents Network to both institutional and individual investors. Individual investors can listen to the call at http://www.fulldisclosure.com, Thomson Reuters individual investor portal, powered by StreetEvents. Institutional investors can access the call via Thomson's password-protected event management site, StreetEvents (http://www.streetevents.com).

Investors may also dial 866.783.2139 and enter the passcode 97752406. A replay of the call will be available for two weeks by dialing 888.286.8010 and entering the passcode 34016526.

About Northfield Laboratories

Northfield Laboratories is a leader in developing a hemoglobin-based oxygen-carrying red blood cell substitute. The initial indication we are seeking for our investigational product PolyHeme is the treatment of life-threatening red blood cell loss when an oxygen-carrying fluid is required and red blood cells are not available. PolyHeme is a solution of chemically modified human hemoglobin that requires no cross-matching and is therefore compatible with all blood types. It has an extended shelf life in excess of 12 months. For further information, visit http://www.northfieldlabs.com.

Northfield Laboratories Inc.
Sophia H. Twaddell, 847-864-3500
Vice President, Corporate Communications
stwaddell@northfieldlabs.com
or
Fleishman-Hillard
Tom Laughran, 312-751-3519
tom.laughran@fleishman.com