GE Healthcare, a unit of General Electric Company (NYSE:GE), and Geron
Corporation (Nasdaq:GERN) today announced that they have entered into a
global exclusive license and alliance agreement to develop and
commercialize cellular assay products derived from human embryonic stem
cells (hESCs) for use in drug discovery, development and toxicity
screening. The program will use stem cells derived from hESC lines
listed on the NIH Human Pluripotent Stem Cell Registry. Financial terms
are not being disclosed.
“This agreement marks a further step in GE Healthcare’s cell technology
strategy aimed at addressing the potential of stem cell applications in
the drug discovery and therapy markets,” said Konstantin Fiedler,
General Manager, Cell Technologies, GE Healthcare. “Combining GE
Healthcare’s reach into the drug discovery and research markets, as well
our expertise in cell manufacturing, with Geron’s expertise and IP in
hESCs, means that together, we will be able to accelerate the
development of hESC-derived products for drug discovery and development.”
“Geron is intensely focused on developing hESC-based cell therapies, and
the expertise that we have developed in scalable manufacturing and
differentiation of hESCs to specific cell types is directly applicable
to the production of these cells for drug discovery,” said David J.
Earp, J.D., Ph.D. Geron’s Senior Vice President of Business Development
and Chief Patent Counsel. “In GE Healthcare we have found the ideal
partner with whom to develop this near-term commercial opportunity.
There is much anticipation of the availability of hESC-derived cells for
drug discovery applications within the pharmaceutical industry and we
look forward to working closely with GE Healthcare to deliver these
promising products.”
Under the terms of the agreement, GE Healthcare has been granted an
exclusive license under Geron’s extensive intellectual property
portfolio covering the growth and differentiation of hESCs, as well as a
sublicense under Geron’s rights to the foundational hESC patents held by
the Wisconsin Alumni Research Foundation. GE Healthcare and Geron have
established a multi-year alliance program under which scientists from
the two companies will work closely together to develop hESC-based
products for drug discovery. The program will use stem cells derived
from hESC lines listed on the NIH Human Pluripotent Stem Cell Registry.