PHILADELPHIA and LONDON, July 1 /PRNewswire/ -- The Healthcare & Science business of Thomson Reuters today announced the availability of three Pharma Matters reports covering the time period January - March 2009. The quarterly Pharma Matters series covers all aspects of the pharmaceutical pipeline, leveraging strategic intelligence and competitive analysis from Thomson Pharma(R), Newport Horizon Premium(TM) and the Thomson Messaging Mapping System(SM).

The Ones to Watch - A Thomson Reuters quarterly review of the latest phase changes in the pharmaceutical pipeline, this report is based on strategic data and analysis from Thomson Pharma, the world's leading pharmaceutical competitive intelligence solution. In the report covering Q1 2009, the top five most promising drugs launched or receiving approval were:

DRUG DISEASE COMPANY

Stelara(TM) Plaque psoriasis Centocor

Gelnique(TM) Overactive bladder Watson Pharmaceuticals

Priligy(TM) Premature ejaculation AZLA Corp

Valdoxen(R) Major depressive disorder Servier, Novartis

Uloric(R) Hyperuricema Teijin, Ipsen, Takeda

More analysis, as well as information on drugs entering clinical Phases I, II and III are available in the full report found here.

Movers and Shakers - This report covers the US generics industry using data and analysis from Newport Horizon Premium, the critical product targeting the global business development system. Analysis from the Q1 2009 report includes:

-- The biggest issue facing the U.S. generics industry this year is the

passage of favorable biogeneric legislation. Other challenges are the

relative lack of funding for foreign inspections conducted by the FDA

and the limited budget of the Office of Generic Drugs. Currently, the

OGD is facing a backlog of work amounting to as much as three years.

-- The median approval time of ANDAs has increased from 18.9 months in

2007 to 21.1 months in 2008.

-- During the first quarter of 2009, Indian companies were in first place

in terms of final ANDA approvals having surpassed the U.S. from the

previous quarter.

-- In the first quarter of 2009, there were Paragraph IV patent challenges

on 21 new active ingredients or combinations, up from eight during the

previous quarter. Telva continues to be, by far, the most prolific

filer of ANDAs with patent challenges.

-- The most active acquirer of Q1 2009 was Sanofi-aventis, purchasing

Zentiva of the Czech Republic for approximately $680 million.

Sanofi-aventis has also announced their acquisition of Laboratorios

Kendrick, one of Mexico's leading generic companies.

To learn more about companies making their mark on the U.S. generics market, click here to read the full report.

Who is Making the Biggest Splash? - A Thomson Reuters expert review of the organizations that are helping to shape professional opinions on drugs and therapies, using the unique insights of the Thomson Message Mapping System. In this quarterly review of the scientific literature on drugs and therapies, Thomson Reuters assesses the quantity and quality of the materials published by pharmaceutical companies, research institutions and other non- commercial bodies. The top five of the 15 listed organizations that have made the biggest impact as the leading sources of information on medical research from January - March 2009 are:

1. Novartis

2. AstraZeneca

3. Pfizer

4. Bristol-Meyers Squibb

5. GlaxoSmithKline

To see the complete list, as well as analysis and methodology, click here to read the full report.

To sign up for the Thomson Reuters Pharma Matters series of publications visit: http://scientific.thomsonreuters.com/info/ matters/.

About Thomson Reuters

Thomson Reuters is the world's leading source of intelligent information for businesses and professionals. We combine industry expertise with innovative technology to deliver critical information to leading decision makers in the financial, legal, tax and accounting, scientific, healthcare and media markets, powered by the world's most trusted news organization. With headquarters in New York and major operations in London and Eagan, Minnesota, Thomson Reuters employs more than 50,000 people in 93 countries. For more information, go to thomsonreuters.com.

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