Sepracor Inc. (Nasdaq: SEPR) will announce its second quarter 2009 financial results on July 24, 2009. In conjunction with the press release, Sepracor will host a conference call and live webcast beginning at 8:30 a.m. ET on July 24, 2009 to discuss its second quarter and first-half 2009 financial results.

To participate via telephone, dial (612) 326-1003 and refer to conference identification number 106718. Please call ten minutes prior to the scheduled conference call time.

For live webcasting, go to the Sepracor web site at www.sepracor.com and access the For Investors section. Click on either the live webcast link or microphone icon to listen. Please go to the web site at least 15 minutes prior to the call in order to register, download, and install any necessary software.

A PDF file of the slides will also be made available in the For Investors section of the web site just prior to the commencement of the webcast.

A replay of the call will be accessible by telephone after completion of the live call and will be available for approximately one week. To replay the call, dial (320) 365-3844 using access code 106718.

Sepracor Inc. is a research-based pharmaceutical company dedicated to treating and preventing human disease by discovering, developing and commercializing innovative pharmaceutical products that are directed toward serving large and growing markets and unmet medical needs. Sepracor's drug development program has yielded a portfolio of pharmaceutical products and candidates with a focus on respiratory and central nervous system disorders. Sepracor's corporate headquarters are located in Marlborough, Massachusetts.

For a copy of this release or any recent release,
visit www.sepracor.com.

Sepracor Inc.
Jonaé R. Barnes, 508-481-6700
Sr. Vice President, Investor Relations and
Corporate Communications