Dedicated UPLC/MS System Solutions Taking on Increased Challenges in Laboratories for Therapeutic Drug Monitoring, Disease Management, Endocrinology, and Toxicology
CHICAGO, July 20 /PRNewswire-FirstCall/ -- At this year's American Association for Clinical Chemistry (AACC) meeting, Waters Corporation (NYSE: WAT) is introducing clinical scientists to its expanded portfolio of new products for clinical and research laboratories including a new research use only (RUO) kit for quantitative measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporin A. A highlight of the AACC meeting, the Waters(R) MassTrak(TM) Immunosuppressants XE RUO Kit provides laboratories an alternative to immunoassay test kits for research laboratory analyses. This and other Waters system platform solutions for amino acid analysis and for vitamin D clinical research laboratories are on display at the AACC Annual Meeting and Clinical Lab Expo, July 19 - 23 in Chicago.
The MassTrak Immunosuppressants XE RUO Kit is for clinical research laboratories seeking an alternative to immunoassay kits for quantitative measurement of immunosuppressant drug levels. Each kit includes reagents, controls, and calibrators, a tuning mixture for the mass spectrometer, and an analytical column for performing up to 500 determinations /kit. Used with Waters ACQUITY TQD System, the MassTrak Immunosuppressants XE RUO Kit achieves high specificity in measuring the target analyte in the presence of drug metabolites and addresses some of the analytical weaknesses of immunoassay immunosuppressant drug measurement.
The new MassTrak Immunosuppressants XE RUO Kit is one of several innovative applications for LC/MS/MS that Waters is spotlighting at AACC 2009.
Vitamin D Analysis
Vitamin D deficiency has been associated with an increased risk of osteoporosis, heart disease, diabetes and other maladies. In the United States testing for vitamin D has increased by 80-90 percent since 2007. For the first time at AACC, Waters will exhibit a system platform optimized for 25-Hydroxyvitamin D analysis for clinical research laboratories. This analytical system and methodology features a robotic liquid handling system and Waters ACQUITY TQD System for high-throughput measurement of total 25-Hydroxyvitamin as well as 25-Hydroxyvitamin D2 and D3.
The test method features a solid-phase extraction sample preparation step that minimizes solvent usage, enhances automation, eliminates the need for solvent evaporation and sample reconstitution. Further information on the new method is included in a new product handout available online from Waters (Part No.
