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BrainStorm Stem Cell Therapy Treatment Shown To Be More Effective Than Other Current Potential Stem Cell Treatments
Monday, November 09, 2009 6:57 AM


Nov. 9, 2009 (Business Wire) -- BrainStorm Cell Therapeutics Inc. (OTCBB:BCLI), a leading developer of adult stem cell technologies and therapeutics, is pleased to announce that the company’s therapeutic approach for treating neurodegenerative diseases was shown to be superior to other current potential stem cell treatments.

In a scientific paper published in the Israel Medical Association Journal, Ofer Sadan, Eldad Melamed and Daniel Offen, from Tel Aviv University, show the migratory capacity of Neurotrophic Factor Stem Cells (NTF-SC) in animal models of Parkinson’s disease and Huntington disease. The study demonstrated that in a rat model for Parkinson’s disease, the efficacy of NTF-SC was superior to that of mesenchymal stem cells in terms of behavioral, biochemical and histological indices.

“The results of this study show that the NTF-SC based treatment is efficacious due to NTF secretion and the stem cell’s migratory capabilities. Since our novel technology is clinically compatible and safe, the study suggests that in the future, cell therapy based on the transplantation of NTF-SC derived from autologous human mesenchymal stem cells should become a preferable option in the treatment of neurodegenerative diseases,” commented Professor Daniel Offen, Brainstorm’s chief scientific advisor.

“This study demonstrates that Brainstorm’s approach in differentiating adult mesenchymal stem cells into NTF-SC, will provide the most effective approach for the treatment of neurodegenerative diseases via the use of stem cells,” said Rami Efrati, CEO of Brainstorm. “As we near clinical trials, the Company and its scientific team will continue to study how our technology and methodology can be further utilized with other neurodegenerative diseases.”

The complete study and scientific paper can be read on Brainstorm’s website at http://www.brainstorm-cell.com/_Uploads/47Sadan2009.pdf.

About BrainStorm Cell Therapeutics, Inc.

BrainStorm Cell Therapeutics Inc. is an emerging company developing adult stem cell therapeutic products, derived from autologous (self) bone marrow cells, for the treatment of neurodegenerative diseases. The patent pending technology is based on discoveries made by the scientific team led by Professor Eldad Melamed, former Head of Neurology at Rabin Medical Center, and cell biologist Prof. Daniel Offen, Head of the Neuroscience Laboratory at the Felsenstein Medical Research Center of Tel-Aviv University. The technology allows for the differentiation of bone marrow-derived stem cells into functional neurons and astrocytes, as demonstrated in animal models. The Company holds rights to develop and commercialize the technology through an exclusive, worldwide licensing agreement with Ramot at Tel Aviv University Ltd., the technology transfer company of Tel-Aviv University.




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