FORM 3UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person*
Bliss Thomas H Jr

(Last)(First)(Middle)
ENTREMED, INC., 9640 MEDICAL CENTER DRIVE

(Street)
ROCKVILLEMD20850

(City)(State)(Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
06/18/2008
3. Issuer Name and Ticker or Trading Symbol
ENTREMED INC [ENMD]
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
SVP, Bus. & Corp. Development
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year) 3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)4. Conversion or Excercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
No securities are beneficially owned

/s/ Cynthia Wong Hu attorney-in-fact for Thomas H. Bliss, Jr.06/19/2008
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

EX-24.3_246441

CONFIRMING STATEMENT

This Statement confirms that the undersigned, Thomas H. Bliss, Jr., has
authorized and designated each of Dane Saglio, Cynthia Wong Hu, and Kathy
Wehmeir-Davis to execute and file on the undersigned's behalf his Form 3, all
Forms 4 and 5 (including any amendments thereto) that the undersigned may be
required to file with the U.S. Securities and Exchange Commission as a result of
the undersigned's ownership of or transactions in securities of EntreMed, Inc.,
The authority of Dane Saglio, Cynthia Wong Hu, and Kathy Wehmeir-Davis under
this Statement shall continue until the undersigned is no longer required to
file Forms 4 and 5 with regard to his ownership of or transactions in securities
of EntreMed, Inc., unless earlier revoked in writing. The undersigned
acknowledges that Dane Saglio, Cynthia Wong Hu, and Kathy Wehmeir-David are not
assuming any of the undersigned's responsibilities to comply with Section 16 of
the Securities Exchange Act of 1934.


Date: 6/19/2008

/s/ Thomas H. Bliss, Jr.
Thomas H. Bliss, Jr.
 



 
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