FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
POSNER BARRY A

(Last)(First)(Middle)
100 CLEARBROOK ROAD

(Street)
ELMSFORDNY10523

(City)(State)(Zip)
2. Issuer Name and Ticker or Trading Symbol
BioScrip, Inc. [BIOS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Executive Vice President
3. Date of Earliest Transaction (Month/Day/Year)
07/08/2008
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, $.0001 par value 07/08/2008 S(1)  10,650 D$ 2.05 113,527 D  

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option $ 6       02/28/2007(2)06/30/2015 Common Stock, $.0001 par value 13,800   13,800 D  
Employee Stock Option $ 2.47       11/01/2007(2)11/01/2016 Common Stock, $.0001 par value 158,587   158,587 D  
Employee Stock Option (Right to Buy Common Stock) $ 6.5        (3)07/06/2008 Common Stock, $.0001 par value 50,000   50,000 D  
Employee Stock Option (Right to Buy Common Stock) $ 4.5        (3)12/02/2008 Common Stock, $.0001 par value 13,166   13,166 D  
Employee Stock Option (Right to Buy Common Stock) $ 12.2       11/28/2002(3)11/28/2011 Common Stock, $.0001 par value 70,000   70,000 D  
Employee Stock Option (Right to Buy) $ 7.95       09/24/2004(3)09/24/2013 Common Stock, $.0001 par value 75,000   75,000 D  
Option to Purchase Common Stock $ 6.52       04/29/2009(2)04/29/2018 Common Stock, $.0001 par value 50,625   50,625 D  
Explanation of Responses:
1. This trade was initiated by UBS to satisfy a margin call and was not initiated by or at the direction of Mr. Posner.
2. Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
3. Fully Vested
/s/ Barry A. Posner07/09/2008
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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