Form 4 Druzgala Pascal For: Aug 17 (10K)

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Druzgala Pascal

(Last)

(First)

(Middle)

C/O ARYX THERAPEUTICS, INC., 6300 DUMBARTON CIRCLE

(Street)

FREMONT

94555

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
ARYx Therapeutics, Inc. [ARYX]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
Sr. V.P. & Chief Scien.Off.

3. Date of Earliest Transaction (Month/Day/Year)
08/17/2009

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	08/17/2009		J⁽¹⁾		8,982	D	⁽⁵⁾	0	I	See footnote ⁽²⁾
Common Stock	08/17/2009		J⁽³⁾		8,982	D	⁽⁵⁾	0	I	See footnote ⁽⁴⁾
Common Stock								172,941	D ⁽⁶⁾
Common Stock								0	I	See footnote ⁽⁷⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security
(Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code
(Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date
(Month/Day/Year)

7. Title and Amount of Underlying Securities
(Instr. 3 and 4)

8. Price of Derivative Security
(Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)

11. Nature of Indirect Beneficial Ownership
(Instr. 4)

Code

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Explanation of Responses:

1. Pursuant to the distribution requirements of the Susan C. Price 2007-1 Grantor Retained Annuity Trust (the "Price Trust"), the reporting person, as Trustee of the Price Trust, transferred 8,982 shares to Susan C. Price, as an individual.

2. Shares were held in the Susan C. Price 2007-1 Grantor Retained Annuity Trust for which reporting person was Trustee. Reporting person disclaimed beneficial ownership of these shares.

3. Pursuant to the distribution requirements of the Peter G. Milner 2007-1 Grantor Retained Annuity Trust (the "Milner Trust"), the reporting person, as Trustee of the Milner Trust, transferred 8,982 shares to Peter G. Milner, as an individual.

4. Shares were held in the Peter G. Milner 2007-1 Grantor Retained Annuity Trust for which reporting person was Trustee. Reporting person disclaimed beneficial ownership of these shares.

5. The value of the shares transferred was based on the closing price of the issuer's stock on July 16, 2009, which was $3.11.

6. The direct holdings of the reporting person give effect to the acquisition of 15,257 shares resulting from the distribution of shares from the Pascal J. Druzgala 2007-1 Grantor Retained Annuity Trust to the reporting person and the purchase by the reporting person of 986 shares under the Company's Employe Stock Purchase Plan on May 14, 2009.

7. The indirect holdings of the reporting person in the Pascal J. Druzgala 2007-1 Grantor Retained Annuity Trust (the "Druzgala Trust") reflect the distribution of 15,257 shares by the Druzgala Trust to the reporting person pursuant to the distribution requirements of the Druzgala Trust.

	/s/ David Nagler (Attorney-in-Fact)	08/19/2009
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

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