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FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Smith Robin L
(Last)(First)(Middle)
C/O NEOSTEM, INC., 420 LEXINGTON AVENUE, SUITE 450
(Street)
NEW YORKNY10170
(City)(State)(Zip)
2. Issuer Name and Ticker or Trading Symbol
NeoStem, Inc. [NBS]		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
CEO and Chairman of the Board
3. Date of Earliest Transaction (Month/Day/Year)
10/29/2009
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code
(Instr. 8)		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		7. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, $0.001 par value per share 10/30/2009 J(1)  74,939 A (1) 797,683 D  
Common Stock, $0.001 par value per share 10/30/2009 A(2)  175,000 A$ 0 972,683 D  

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date
(Month/Day/Year)		7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		11. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Options (right to buy) $ 2.04 10/29/2009 A(3)  750,000   (3)10/28/2019 Common Stock, par value $0.001 per share 750,000 $ 0 750,000 D  
Common Stock Warrants (right to buy) $ 8 10/30/2009 D(4)   20,000  (5)01/25/2014 Common Stock, par value $0.001 per share 20,000 (4) 0 D  
Common Stock Warrants (right to buy) $ 6.1818 10/30/2009 A(4)  20,000   (5)01/25/2014 Common Stock, par value $0.001 per share 20,000 (4) 20,000 D  
Common Stock Warrants (right to buy) $ 8 10/30/2009 D(4)   2,000  (6)02/05/2014 Common Stock, par value $0.001 per share 2,000 (4) 0 D  
Common Stock Warrants (right to buy) $ 6.1818 10/30/2009 A(4)  2,000   (6)02/05/2014 Common Stock, par value $0.001 per share 2,000 (4) 2,000 D  
Common Stock Warrants (right to buy) $ 8 10/30/2009 D(4)   2,500  (7)06/01/2011 Common Stock, par value $0.001 per share 2,500 (4) 0 D  
Common Stock Warrants (right to buy) $ 6.1818 10/30/2009 A(4)  2,500   (7)06/01/2011 Common Stock, par value $0.001 per share 2,500 (4) 2,500 D  
Common Stock Warrants (right to buy) $ 8 10/30/2009 D(4)   927  (8)08/29/2011 Common Stock, par value $0.001 per share 927 (4) 0 D  
Common Stock Warrants (right to buy) $ 6.1818 10/30/2009 A(4)  927   (8)08/29/2011 Common Stock, par value $0.001 per share 927 (4) 927 D  
Stock Options (right to buy) $ 5.3 10/30/2009 D(9)   10,000  (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  10,000   (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 10,000 D  
Stock Options (right to buy) $ 8 10/30/2009 D(9)   10,000  (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  10,000   (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 10,000 D  
Stock Options (right to buy) $ 10 10/30/2009 D(9)   10,000  (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  10,000   (10)06/01/2016 Common Stock, par value $0.001 per share 10,000 (9) 10,000 D  
Stock Options (right to buy) $ 16 10/30/2009 D(9)   12,000  (11)06/01/2016 Common Stock, par value $0.001 per share 12,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  12,000   (11)06/01/2016 Common Stock, par value $0.001 per share 12,000 (9) 12,000 D  
Stock Options (right to buy) $ 25 10/30/2009 D(9)   12,000  (12)06/01/2016 Common Stock, par value $0.001 per share 12,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  12,000   (12)06/01/2016 Common Stock, par value $0.001 per share 12,000 (9) 12,000 D  
Stock Options (right to buy) $ 6 10/30/2009 D(9)   10,000  (13)12/04/2016 Common Stock, par value $0.001 per share 10,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  10,000   (13)12/04/2016 Common Stock, par value $0.001 per share 10,000 (9) 10,000 D  
Stock Options (right to buy) $ 6 10/30/2009 D(9)   5,000  (14)12/04/2016 Common Stock, par value $0.001 per share 5,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  5,000   (14)12/04/2016 Common Stock, par value $0.001 per share 5,000 (9) 5,000 D  
Stock Options (right to buy) $ 5 10/30/2009 D(9)   55,000  (15)01/17/2017 Common Stock, par value $0.001 per share 55,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  55,000   (15)01/17/2017 Common Stock, par value $0.001 per share 55,000 (9) 55,000 D  
Stock Options (right to buy) $ 4.95 10/30/2009 D(9)   150,000  (16)09/26/2017 Common Stock, par value $0.001 per share 150,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  150,000   (16)09/26/2017 Common Stock, par value $0.001 per share 150,000 (9) 150,000 D  
Stock Options (right to buy) $ 4.95 10/30/2009 D(9)   100,000  (17)09/26/2017 Common Stock, par value $0.001 per share 100,000 (9) 0 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(9)  100,000   (17)09/26/2017 Common Stock, par value $0.001 per share 100,000 (9) 100,000 D  
Stock Options (right to buy) $ 1.9 10/30/2009 A(18)  229,678  10/30/200910/29/2016 Common Stock, par value $0.001 per share 229,678 $ 0 229,678 D  
Explanation of Responses:
1. The reporting person received 74,939 shares of common stock, $0.001 par value per share ("Common Stock"), of NeoStem, Inc. (the "Company") in exchange for 389,966 shares of common stock, par value $0.01, of China Biopharmaceuticals Holdings, Inc. ("CBH") on October 30, 2009 in connection with the merger (the "Merger") of CBH with and into CBH Acquisition LLC, a wholly-owned subsidiary of the Company, at an exchange ratio of 0.1921665. On the effective date of the Merger, the closing price of the Company's common stock was $1.90 per share, and the closing price of CBH's common stock was $0.30 per share.
2. The reporting person was granted 175,000 shares of Common Stock on October 30, 2009, the effective date of the Merger, pursuant and subject to the Company's 2009 Equity Compensation Plan (the "2009 Plan"). These shares vested in full on the date of grant.
3. The reporting person was granted an option to purchase 750,000 shares of Common Stock on October 29, 2009, pursuant and subject to the 2009 Plan. The option is scheduled to vest as to 250,000 shares on the achievement of a specified business milestone, as to an additional 250,000 shares on July 8, 2010 and as to the remaining 250,000 shares on July 8, 2011.
4. Each pair of reported transactions involved an amendment to the exercise price of an outstanding warrant to purchase shares of Common Stock, resulting in the deemed cancellation of the "old" warrant and the issuance of a replacement warrant. In each case the expiration date has been maintained. The amendment to the exercise price was effected pursuant to approval received from the Company's stockholders ("Stockholder Approval") at its Special Meeting of Stockholders held on October 29, 2009 (the "Special Meeting") and as described in the Company's Proxy Statement/Prospectus on Form S-4/A filed with the Securities and Exchange Commission on October 6, 2009 (the "Form S-4").
5. The warrant was acquired on January 26, 2007 in a private placement and was fully exercisable as of that date.
6. The warrant was acquired on February 6, 2007 in a private placement and was fully exercisable as of that date.
7. The warrant was acquired on June 2, 2006 and was fully exercisable as of that date.
8. The warrant was acquired on August 30, 2006 and was fully exercisable as of that date.
9. Each pair of reported transactions involved an amendment of the exercise price of an option outstanding under the Company's 2003 Equity Participation Plan (the "2003 Plan"), resulting in the deemed cancellation of the "old" option and the grant of a replacement option pursuant and subject to the 2003 Plan, as amended. In each case the expiration date and vesting schedule have been maintained. The amendment to the exercise price was effected pursuant to Stockholder Approval received at the Special Meeting and as described in the Form S-4.
10. The option was granted on June 2, 2006 and vested in its entirety on the date of grant.
11. The option was granted on June 2, 2006 and vested on June 2, 2007.
12. The option was granted on June 2, 2006 and vested on June 2, 2008.
13. The option was granted on December 5, 2006 and vested in its entirety upon the date of grant.
14. The option was granted on December 5, 2006 and vested on August 9, 2007.
15. The option was granted on January 18, 2007 and vested as to (i) 25,000 shares upon the first closings of the Company's January 2007 private placement, (ii) 15,000 shares on June 30, 2007 and (iii) 15,000 shares on December 31, 2007.
16. The option was granted on September 27, 2007 and vested in its entirety on the date of grant.
17. The option was granted on September 27, 2007 and vested in its entirety on October 30, 2009, upon the consummation of the Merger.
18. Effective on October 30, 2009, the reporting person was granted an option to purchase 229,678 shares of common stock of the Company, pursuant and subject to the 2009 Plan and Stockholder Approval received at the Special Meeting to issue discretionary grants in connection with the option repricing as described in the Form S-4. This option vested in its entirety on the date of grant.
Robin L. Smith, By: /s/ Catherine M. Vaczy, Esq., Attorney-in-Fact11/02/2009
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

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